Patient Follow-up
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History eliciting symptoms and physical examination every 3-6 months for 3 years , then 6-12 months for 3 years, then annually with attention paid to long term side-effects (osteoporosis). |
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Ipsilateral and contralateral radiology every year. |
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Not routinely recommended for asymptomatic patients: blood counts; chemistry, chest Xray, bone scan, liver ultrasound, chest scans of chest or abdomen and any tumour marker such as CA 153, CEA are not recommended. |
Tumour Markers
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Serum tumour markers should be used only as a guide to aid treatment decisions and monitor response of not easily measurable disease in the metastatic breast cancer settings and not for screening or diagnosis. |
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The proliferation marker Ki-67 provides important prognostic, particularly for patients with small tumours and no axillary node involvement. |
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Oestrogen and progesterone receptors and their degree of positive are excellent predictors of response in all patients with breast cancer and aid the multi-disciplinary team as to which hormonal therapy should be used. |
Over-expression of the Her-2/neu protein is associated with poor prognosis and can be used to select patients for trastuzumab (Herceptin) therapy. |